Flavonoids in Astragalus corniculatus

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The Flavonoids of Lotus corniculatus

Since the first studies published in the fifties and sixties (Nakaoki et al., 1956; Harney and Grant, 1964; Bate-Smith, 1965), many authors have investigated the flavonoid chemistry of Lotus corniculatus (Table 1 and Table 2) and demonstrated the richness and diversity of flavonoid compounds in this species. Some authors have examined the variation with altitude of the flavonoid content of Lotu...

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Effect of Purified Saponin Mixture from Astragalus corniculatus on Toxicity Models in Isolated Rat Hepatocytes

A purified saponin mixture (PSM) isolated from Astragalus corniculatus Bieb. (Fabaceae) was investigated for its protective effect in two models of toxicity, carbon tetrachloride (CCl4) and tert-butyl hydroperoxide (t-BuOOH), using isolated rat hepatocytes. CCl4 undergoes dehalogenation in the liver endoplasmic reticulum. This process leads to trichlormethyl radical (CCl3) formation, initiation...

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Flavonoids and phenol carboxylic acids in the oriental medicinal plant Astragalus membranaceus acclimated in Poland.

Astragalus membranaceus (Fisch.) Bunge has been was successfully acclimated in Central Europe. We report the content of isoflavones and some other polyphenolic compounds in roots and aerial parts that have been analyzed by means of TLC and HPLC. The total amount of isoflavones in leaves, was 0.55 mg g(-1) dry weight, and of the flavonols--up to 3.54 mg g(-1). In the roots isoflavonoid content w...

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Induction of apoptosis in human hepatocarcinoma SMMC-7721 cells in vitro by flavonoids from Astragalus complanatus.

AIM OF THE STUDY Flavonoids extracted from the seeds of Astragalus complanatus R.Br. reduce the proliferation of many cancer cells. The present study was carried out to evaluate the effects of these flavonoids from Astragalus complanatus (FAC) on human hepatocarcinoma cell viability and apoptosis and to investigate its mechanisms of action in SMMC-7721 cells. MATERIALS AND METHODS Cell viabil...

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In Vivo and in Vitro Immunomodulatory and Anti-inflammatory Effects of Total Flavonoids of Astragalus

BACKGROUND Astragali Radix has long been used to improve immune function in traditional Chinese medicine. However, its main active components and potential immunomodulatory or anti-inflammatory activities have not been elucidated. In the present study, the immunomodulatory and anti-inflammatory activities of total flavonoids of Astragalus (TFA) isolated from Astragali Radix were evaluated by us...

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ژورنال

عنوان ژورنال: Química Nova

سال: 2008

ISSN: 0100-4042

DOI: 10.1590/s0100-40422008000100012